The question of the right dosage, as well as the type and duration of application, is very difficult to answer. Since there is no scientificresearch showing how STH should be taken for performance improvement, we can only rely on empirical data, that is experimental values. The respective manufacturers indicate that in cases of hypophysially stunted growth due to lacking or insuffieient release of growt hormones by the hypophysis, a weekly average dose of 0.3 I.U/ week per pound of body weight should be taken. An athlete weighting 200 pounds, therefore, would have to inject 60 I.U. weekly. The dosage would be divided into three intramuscular injections of 20 I.U. each. Subcutaneous injections (under the skin) are another form of intake which, however would have to be injected daily, usually 8 I.U. per day. Top athletes usually inject 8-20 I.U./day. Ordinarily, daily subcutaneous injections are preferred. Since STH has a half life time of less than one hour, it is not surprising that some athletes divide their dail dose into three or four subcutaneous injections of 2-4 I.U. each. Application of regular small dosages seems to bring the most effective results.Effective Dose: 100 - 300 mg/week What does this tell us? The information on this site is not intended to substitute for professional medical advice. Be sure to contact your physician, pharmacist or other health care provider for more information about this medication.Clenbuterol should therefore be used primarily for fat loss and cutting purposes. American athletes have a long a fond relationship with Testosterone cypionate. While testosterone enanthate is manufactured widely throughout the world, cypionate seems to be almost exclusively an American item. It is therefore not surprising that American athletes particularly favor this testosterone ester. But many claim this is not just a matter of simple pride, often swearing cypionate to be a superior product, providing a bit more of a "kick" than enanthate. At the same time it is said that Testosterone cypionate produces a slightly higher level of water retention, but not enough for it to be easily discerned. Of course when we look at the situation objectively, we see these two steroids are really interchangeable, and cypionate is not at all superior. Both are long acting oil-based injectables, which will keep tesosterone levels sufficiently elevated for approximately two weeks. Enanthate may be slightly better in terms of testosterone release, as this ester is one carbon atom lighter than cypionate (remember the ester is calculated in the steroids total milligram weight). The difference is so insignificant however that no one can rightly claim it to be noticeable (we are maybe talking a few milligrams per shot).The empirical formula for tadalafil is C22H19N3O 4, and its official organic name is (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a- hexahydro-2-methyl-pyrazino[1 ,2 :1,6]pyrido[3,4-b]indole-1,4-dione. The molecular weight is 389.41. Tadalafil tablets are yellow, film-coated, and almond-shaped, and are produced in 5, 10, or 20 mg doses. EPO is a primary growth product in which it regulates red blood cell formation in the body. This is highly liked by long distance runners and overall endurance athletes. The red blood cell production, which involves removing and storing a quantity of blood to later replace it when in need for the transport of oxygen more efficiently, which gives the athlete a much increased boost.EPO's chemical blood doping procedure can come with its own problems with cell volume can be very dangerous, where cell concentration can reach life threatening point if the drug is used incorrectly resulting in heart attack, stroke, seizure even death. So one must be very cautious and be overlooked by a doctors assistance.Each 10ml multidose vial contains 50mg per ml or 100mg per ml and comes with a white coloured top. Appetite stimulation, Osteoporosis, increased bone density,recovery from major surgery and trauma. By minimizing the production of DHT, we should greatly reduce many of these harsh side effects and make our testosterone cycles more comfortable. In many instances, Proscar/Propecia can allow the athlete the use of steroid compounds (testosterone esters such as cypionate, enanthate, Sustanon etc.), Halotestin and methyltestosterone with much less androgenic side activity.Effective Dose: 20-50 mg/day. Reductil (Sibutramine)
Because of the risk of birth defects, there are strict rules for the females who could get pregnant to use Roaccutane. "In a study to be published today in the journal Science. scientists at Duke University Medical Center said they have found that the reaction of breast cells to tanoxifen changes over time until the drug starts to behave like the hormone it is supposed to block."As with all testosterone products, SUSTOR 250 is a strong anabolic with pronounced androgenic activity. It is most commonly used as a bulking drug, providing exceptional gains in strength and muscle mass. Although it does convert to estrogen, as is the nature of testosterone, this injectable is noted as being slightly more tolerable than cypionate or enanthate. As stated throughout this book, such observations are only issues of timing however. With Sustanon, blood levels of testosterone are building more slowly, so side effects do not set in as fast. For equal blood hormone levels however, testosterone will break down equally without regard to ester. Many individuals may likewise find it necessary to use an antiestrogen, in which case a low dosage of Nolvadex (tamoxifen citrate) or Proviron (mesterolone) would be appropriate. Also correlating with estrogen, water retention should be noticeable Sustanon. This is not desirable when the athlete is looking to maintain a quality look to the physique, so this is certainly not an idea drug for contest preparation.The down side is that this drug is responsible for a number of side effects. It is an alpha alkylated 17 compound, which is quite toxic to the liver. Average dosages for Dianabol have been in the range of 15mg to 30mg a day oral or 50mg to 100mg a week by injection. Regarded by many athletes as being one of the most effective oral steroids ever produced. It was not known as the "Breakfast of Champions" for nothing. Dianabol is still one of the most effective strength and size building oral steroids probably second only to Anadrol 50 but it is not as harsh on the system as Anadrol 50 is.Proviron is the Schering brand name for the oral androgen mesterolone (1 methyl-dihydrotestosterone). Just as with DHT, the activity of Proviron is that of a strong androgen which does not aromatize into estrogen. In clinical situations Proviron is generally used to treat various types of sexual dysfunction, which often result from a low endogenous testosterone level. Proviron can usually reverse problems of sexual disinterest and impotency, and it is sometimes used to increase the sperm count. Proviron does not stimulate the body to produce testosterone, but mesterolone is simply an oral androgen substitute that is used to compensate for a lack of the natural male androgen. Although mesterolone is strongly androgenic, the anabolic effect of Proviron is considered too weak for muscle building purposes.An antiaromatase would not correct the estrogenic problems of this drug, since it is directly estrogenic, not requiring conversion by aromatase. An antiestrogen such as Clomid would probably help, but since methandriol is a poor anabolic anyway, there is no point to a methandriol/Clomid stack. It´s relatively high cost is its only major drawback when you buy Bonavar. Tablets can typically sell in Mexico or on the black market for up to a dollar (1USD) per 10mgs. Many black market dealers or Underground Labs, however offer capsules, liquid form (or in some cases, even their own brand of tabs) for substantially less money than the legit pharmaceutical versions, or even veterinary versions found overseas.Take diazepam tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. If diazepam upsets your stomach, take it with food or milk. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice. Rifampin is a potent hepatic enzyme inducer and can accelerate the hepatic metabolism of diazepam. Patients should be monitored closely for signs of reduced diazepam effects if given rifampin concomitantly.Drug Class: Leutenizing Hormone (LH) - Gonadotropin Triolandren 20 mg/ml; Ciba Geigy CH Clenbuterol itself, is a third generation beta agonist. Clenbuterol's use as a bodybuilding drug item from a number of medical reviews which have cited its outstanding potential to promote muscle gains as well as fat loss. It has been used in parts of England for several years by a limited number of elite athletes. More recently, due to the steroid crackdown, there have been an increasing number of American bodybuilders that are experimenting with this drug. Clenbuterol is indeed the most intriguing ergogenic aid I have studied with the sole exception of anabolic steroids.Kidney or liver disease — Higher blood levels of benzodiazepines may result, increasing the chance that side effects will occur Always use a sterile needle and syringe every time and a clean injecting technique (e.g. don't touch the needle or the skin where you are going to inject, with your fingers and don't breathe on or cough over the injection site before or after injecting). Testosterone´s anabolic/androgenic ratio is 1:1 meaning it is exactly as anabolic as it is androgenic. Actually, testosterone is the steroid which all anabolic/androgenic ratio´s are based on. If a steroid is 2:1, then it is, compared with testosterone´s ratio, doubly as anabolic as it is androgenic. Hence, we see from testosterone´s ratio, it is both quite anabolic as well as androgenic.Available Doses: 5,20,24,25,50 or 100 mcg tabs, 20 mcg/ml injection I’m not sure where to begin. This study has the potential to completely change the way we age. Testosterone suspension: More Information Equipoise® can also produce distinct androgenic side effects. Incidences of oily skin, acne, increased aggression and hair loss are likewise all possible with this compound, although will typically be related to the use of higher doses. Women in fact find this drug quite comfortable, virilization symptoms usually unseen when taken at low doses. Boldenone does reduce to a more potent androgen (dihydroboldenone) via the 5alpha reductase enzyme (which produces DHT from testosterone), however its affinity for this interaction in the human body is low to nonexistent". We therefore cannot consider the reductase inhibitor Proscar® to be of much use with Equipoise, as it would be blocking what is at best an insignificant path of metabolism for the steroid. And although this drug is relatively mild, it may still have a depressive effect on endogenous testosterone levels. A combination of HCG and Clomid®/Nolvadex® may likewise be needed at the conclusion of each cycle to avoid a "crash", particularly when running long in duration.Caverject (Alprostadil) Impulse Kit Information World wide Deca is one of the most popular injectable steroids. It's popularity is likely due to the fact that Deca exhibits significant anabolic effects with minimal androgenic side effects.Keep stanozolol in a tightly closed container and out of reach of children. Store stanozolol at room temperature and away from excess heat and moisture (not in the bathroom). To some extent, nandrolone aromatizes to estrogen, and it does not appear that this can be entirely blocked by use of aromatase inhibitors – indeed, aromatase may not be involved at all in this process (there is no evidence in humans that such occurs) with the enzyme CYP 2C11 being in my opinion the more likely candidate for this activity. In any case, Cytadren, an aromatase inhibitor, has not been found effective in avoiding aromatization of nandrolone.2. Before starting Roaccutane Treatment If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up. Sexual activity may put extra strain on your heart, especially if you have heart problems, if you have heart problems and experience any serious side effects while having sex, stop having sex and tell your doctor immediately. These side effects include severe dizziness, fainting, chest pain, or nausea. In the unlikely event that you have a painful or prolonged erection (lasting more than 4 hours), stop using this medicine and seek immediate medical attention or permanent problems could occur.You should be aware that Provironum is also an estrogen antagonist which prevents the aromatization of steroids. Unlike the antiestrogen Nolvadex which only blocks the estrogen receptors (see Nolvadex) Provironum already prevents the aromatizing of steroids. Therefore gynecomastia and increased water retention are successfully blocked. Since Provironum strongly suppresses the forming of estrogens no re-bound effect occurs after discontinuation of use of the compound as is the case with, for example, Nolvadex where an aromatization of the steroids is not prevented. One can say that Nolvadex cures the problem of aromatization at its root while Nolvadex simply cures the symptoms. For this reason male athletes should prefer Provironum to Nolvadex. With Provironum the athlete obtains more muscle hard-ness since the androgen level is increased and the estrogen concen-tration remains low. This, in particular, is noted positively during the preparation for a competition when used in combination with a diet. Female athletes who naturally have a higher estrogen level of-ten supplement their steroid intake with Provironum resulting in increased muscle hardness. In the past it was common for body-builders to take a daily dose of one 25 mg tablet over several weeks, sometimes even months, in order to appear hard all year round. This was especially important for athletes' appearances at guest performances, seminars and photo sessions. Today Clenbuterol is usually taken over the entire year since possible virilization symp-toms cannot occur which is not yet the case with Provironum. Since Provironum is very effective male athletes usually need only 50-mg/ day which means that the athlete usually takes one 25 mg tablet in the morning and another 25 mg tablet in the evening. In some cases one 25 mg tablet per day is sufficient. When combining Provironum with Nolvadex (50 mg Provironum/day and 20 mg Nolvadex/day) this will lead to an almost complete suppression of estrogen. Even better results are achieved with 50 mg Provironum/ day and 500 - 1000 mg Teslac/day. Since Teslac is a very expensive compound (see Teslac) most athletes do not consider this com-bination.• It improves resistance to common illness- (73%) Don't use a medium or long acting insulin in the middle or latter part of the day, as you may very well experience a hypoglycemic attack whilst you are asleep. If this happens, neither you nor anyone else will be aware of or able to respond to your urgent need for glucose, in order to prevent possible serious harm.HCG:Human Chorionic Gonadotropin is a drug used to jump start the body's production of testosterone after the end of a steroid cycle. It act in the body by imitating the action of LH (a hormone that regulated testosterone production). Clenbuterol is a prescribed asthma medication which is catabolic to fat and anabolic to muscle. Clenbuterol is not a steroid hormone but a beta-2-symphatomimetic.Testosterone heptylate is another injectable testosterone ester. The French pharmaceutical Company Laboratoire Theramex is the only firm worldwide which manufactures this compound and has been selling it under the drug name Testosterone Heptylate Theramex since 1955. Testosterone Heptylate Theramex rates high among French, Belgian, and Dutch athletes since it is readily available, extremely economical, and very effective - The compound Testosterone heptylate, like every injectable testosterone, has a strong androgenic effect which goes hand in hand with a distinct anabolic component.It is best to use some kind of birth control while you are taking tamoxifen and for about 2 months after you stop taking Nolvadex C&K. However, do not use oral contraceptives since they may interfere with tamoxifene. Tell your doctor right away if you think you have become pregnant while taking Nolvadex C&K. Used to come off of a steroid cycle. Take with Nolvadex to reduce side effects. The most common side effects with CIALIS were headache and upset stomach. Backache and muscle ache were also reported, sometimes with delayed onset. Most men weren't bothered by the side effects enough to stop taking CIALIS. Although a rare occurrence, men who experience an erection for more than 4 hours (priapism) should seek immediate medical attention. Discuss your medical conditions and medications with your doctor to ensure CIALIS is right for you and that you are healthy enough for sexual activity.Please discuss the treatment with your doctor again if any of the conditions above apply to you. A number of athletes claim that GH is not that effective on its own, but in a stack with steroids it can do remarkable things. Perhaps there is some type of actual synergism created by the concomitant use of these two agents. Empirical data suggests that the efficacy of GH is dose related and that the majority of users may not have been taking enough of it to get positive results. Despite speculation concerning its efficacy, synthetic GH is being used by thousands of elite athletes. These include men and women bodybuilders, strength athletes, as well as a multitude of Olympic competitors. Although Growth Hormone is banned by athletic committees, there is no method for the detection of it which allows drug tested competitors to use this product freely without any ramifications. Adverse reactions to GH use are rare but technically could involve acromegaly (elongation of the feet, forehead and hands). Other possible side effects involve overgrowth of the elbows or jaw, thickening of the skin and a type of diabetes. There are numerous counterfeit versions of this product which are merely cashing in on the drug's mystique and high price tag. The legitimate versions must be refrigerated at all times, before and after they are reconstituted. Effective dosages seem to be in the area of 2 I.U., 2-4 times a week. Cycle length is usually determined by how long the athlete can afford it. Some take the product for 6 week cycles, others use it year round.What is more interesting to me is the role of NO on muscles during resistance training. JE Anderson found that NO appears to be a vital signal in the activation of muscle satellite cells in response to damage. Satellite cell activation is the key first step in the repair and hypertrophy of muscle cells after heavy training. Viagra may therefore enhance the hypertrophy response to exercise, working at the most basic and primary level of the process. So you see, the longer the ester on the testosterone is, the longer the steroid is active in your body, and the less actual test you get. This is because, for every 100mgs of testosterone cypionate you inject, only 69.90mgs of it is actually testosterone, the rest is the cypionate ester, which must be removed. On the other hand, with the propionate ester you´ll get 83.72mgs of Testosterone! The advantage to longer esters is that they need to be injected less frequently (test prop needs to be injected every other day while you can shoot test cyp once a week). The disadvantage to long estered steroids is that they contain less actual steroid. Anecdotally, however, most people from Steroid.com and other discussion boards who have tried differing esters on their various cycles agree: Testosterone Propionate causes the least side effects and the least bloating. For this reason, it´s often the testosterone of choice in cutting cycles. On a personal note, it´s the only form of testosterone I ever use, and it´s the only one most women will use, due to the previously mentioned factors (as well as it´s ability to clear your body quickly upon cessation in the case of side effects). Testosterone levels when you´re using injectable testosterone propionate begin to decline sharply after the second day of use(5). Obviously this is not the drug of choice for those who are squeamish about injections, you´ll be shooting this stuff every other day at least.Effective Dose: 1IU per 10-20 lbs. of body weight. Use clenbuterol with caution in hypersensitive and diabetic individuals and in individuals with latent or clinically recognized angle closure glaucoma, coronary artery disease, congestive heart failure, prostatic hypertrophy, hyperthyroidism, urinary retention. Andropen contains 20mgs of Testosterone Acetate, 75mgs of Testosterone Cypionate, 90mgs of Testosterone Decanoate, and 40mgs each of Testosterone Propionate and Phenylpropionate in a 20ml bottle. I am very impressed with the fact that this product appears to be designed specifically for bodybuilders and athletes, and certainly if I wanted to create a long, medium, and short estered testosterone product, it would be something like this one. Also, due to that fact, I think I´d recommend shooting it EOD, or E3D or so& .giving you a very decent and relatively stable level of hormone in your body. A few years back, I made a testosterone blend for my own use out of powders, which was essentially a five estered testosterone (the same esters as Sust + 100mgs of test with the Cypionate ester per milliliter). Anyway, now it seems that every Underground Lab is involved with this type of thing. It´s not uncommon to see a price list with several "custom blends" or "house blends" of various estered testosterone´s (or sometimes Trenbolones, or whatever).Formula: C19H30O3 Durabolin is very similar to the popular Deca-Durabolin. Durabolin must be injected frequently and in regular intervals. The substance nandrolone-phenylpropionate quickly gets into the blood, where it remains active for two to three days. Athletes who hope for optimal results inject Durabolin every third day, or even every two days. The dosage is around 50-100 mg per injection, or a total of 150-300 mg/week. Those who have access to the 50 mg version should take advantage of it since it is less expensive than the 25 mg version, which is normally more easily available. in addition, the 1-2 ml injections are more pleasant than the 2-4 ml. Durabolin has a distinct anabolic effect which assists the protein synthesis and allows the protein to be stored in the muscle cell in large amounts. This is combined with a moderate androgenic component which stimulates the athlete's regeneration and helps maintain the muscle mass during a diet. It shows that Durabolin stores much less water in the body than Deca-Durabolin. For this reason, Durabolin is more suitable for a preparation for a competition while Deca should be given preference for the buildup of strength and muscle mass. Durabolin, however, can be used for this purpose as well. The gains are fewer and slower than with Deca but of a higher quality and remain, for the most part, after discontinuing the com-pound. A stack suitable for this purpose would be, e.g. 56 mg Durabolin every 2 days, 50 mg Testosterone Propionate every days, and 20 mg Winstrol tablets every day.Stanozolol also plays a role in strong adverse changes in HDL/LDL cholesterol levels, especially with the oral form because of the method of administration, which may cause concern for this side effect. Combination with Proviron to the test cycle should prove useful by enhancing the free state of this potent muscle building androgen. Each 10 ml multidose vial contains 75mg per ml. Vials have a white coloured generic flip-off top. Clomiphene Citrate (Clomid®): Description Apnea, hypotension, and cardiac arrest have been reported following parenteral administration of benzodiazepines to the elderly, severely ill patients, or patients with compromised respiratory function. Respiratory depression also has occurred in these patients during benzodiazepine therapy, occasionally resulting in death.Women should not use dianabol because considerable virilization symptoms can occur. The side effects of Proviron in men are low at a dosage of 2-3 tablets/day so that Proviron, taken for example in combination with a steroid cycle, can be used comparatively without risk over several weeks. Since Proviron is well-tolerated by the liver liver dysfunctions do not occur in the given dosages. For athletes who are used to acting under the motto "more is better" the intake of Proviron could have a paradoxical effect. The most common side effect of Proviron-or in this case, secondary symptom- is in part a distinct sexual overstimulation and in some cases continuous penis erection. Since this condition can be painful and lead to possible damages, a lower dosage or discontinuing the compound are the only sensible solutions. Female athletes should use Proviron with caution since possible androgenic side effects cannot be excluded. Women who want to give Proviron a try should not take more than one 25 mg tablet per day. Higher dosages and periods of intake of more than four weeks considerably increase the risk of virilization symptoms. Female athletes who have no difficulties with Proviron obtain good results with 25 mg Proviron/day and 20 mg Nolvadex/day and, in combination with a diet, report an accelerated fat breakdown and continuously harder muscles.Day 6 - Day 12: 100 mcg Blurring or other visual symptoms such as spots or flashes may occasionally occur during therapy with Clomid. These visual symptoms increase in incidence with increasing total dose or therapy duration and generally disappear within a few days or weeks after Clomid is discontinued. These visual symptoms may render such activites as driving a car or operating machinery more hazardous than usual, particularly under conditions of variable lighting.Substance: 40mg Nandrolone Phenylpropionate & 60mg Nandrolone Decanoate per ml. Stanozolol has some unique biochemical properties which we will discuss in a later article. Proviron is an anti-aromatase, so obviously anti-estrogens would be futile and redundant. Blood pressure medication for those prone to hypertension may be wise, as this DHT can increase the blood pressure. Insulin is used in a wide variety of ways. Most athletes choose to use it immediately after a workout. Dosages used are usually 1 IU per 10-20 pounds of lean bodyweight. First-time users should start at a low dosage and gradually work up. For example, first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout. This will allow the athlete to safely determine a dosage. Insulin dosages can vary significantly among athletes and are dependent upon insulin sensitivity and the use of other drugs. Athletes using growth hormone and thyroid will have higher insulin requirements, and therefore, will be able to handle higher dosages. |
PRODUCT NAME: Oxydrol
SUBSTANCE: Oxymetholone
CONTENT: 100 Tabs/50mg
MANUFACTURER: British Dragon / Thailand
Oxydrol is the only oral anabolic-androgenic steroid indicated in the treatment of anemias caused by deficient red cell production. Oxymetholone is contraindicated in: male patients with carcinoma of the prostate or breast; females with hypercalcemia with carcinoma of the breast, women who are or may become pregnant; ipatients with nephrosis or the nephrotic phase of nephritis; patients with hypersensitivity to the drug or with severe hepatic dysfunction.
Anadrol (Oxydrol) is the U.S. brand name for oxymetholone, a very potent oral androgen. This compound was first made available in 1960, by the international drug firm Syntex. Since oxymetholone is quite reliable in its ability to increase red blood cell production (and effect characteristic of most anabolic/androgenic steroids), it showed great promise in treating cases of severe anemia. It turned out to be well suited for this purpose, and was popular for quite some time. But recent years have brought fourth a number of new treatments, most notably the non-steroidal hormone Epogen (erythropoietin). This drug is shown to have a much more direct effect on the red blood cell count, without the side effects of a strong androgen. Syntex stopped in the U.S. in 1993, which was around the same time they decided to drop this item in a number of foreign countries as well. Plenastril from Switzerland and Austria was dropped; following soon was Oxitosona from Spain. Many Athletes feared Anadrol 50 might be on the way out for good. But new HIV/AIDS studies have shown a new light on oxymetholone. These studies are finding (big surprise) exceptional anti-wasting properties to the compound and believe it can be used safely in many such cases. Interest has been peaked, and as of 1998 Anadrol 50 is again being sold in the United States. This time we see the same Anadrol 50 brand name, but the manufacturer is the drug firm Unimed. Syntex continues to market & license this drug in a number of countries however (under a few different brand names).
Anadrol (Oxydrol) is considered by many to be the most powerful steroid available, with results of this compound being extremely dramatic. A steroid novice experimenting with oxymetholone is likely to gain 20 to 30 pounds of massive bulk, and it can often be accomplished in less than 6 weeks, with only 50-100mg a day. This steroid produces a lot of trouble with water retention, so let there be little doubt that much of this gain is simply bloat. But for the user this is often little consequence, feeling bigger and stronger on Anadrol 50 than any steroid they are likely to cross. Although the smooth look that results from water retention is often not attractive, it can aid quite a bit to the level of size and strength gained. The muscle is fuller, will contract better and is provided a level of protection in the form of "lubrication" to the joints as some of this extra water is held into and around connective tissues. This will allow for more elasticity, and will hopefully decrease the chance for injury when lifting heavy. It should be noted however, that on the other hand the very rapid gain in mass might place too much stress on your connective tissues for this to compensate. The tearing of pectoral and biceps tissue is commonly associated with heavy lifting while massing up on heavy androgens. There is such a thing as gaining too fast. Pronounced estrogen trouble also puts the user at risk for developing gynecomastia. Individuals sensitive to the effects of estrogen, or looking to retain a more quality look, will therefore often add Nolvadex to each cycle.
It is important to note however, that this drug does not directly convert to estrogen in the body. Oxymetholone is a derivative of dihydrotestosterone, which gives it a structure that cannot be aromatized. As such, many have speculated as to what makes this hormone so troublesome in terms of estrogenic side effects. Some have suggested that it has progestational activity, similar to nandrolone, and is not actually estrogenic at all. Since the obvious side effects of both estrogens and progestins are very similar, this explanation might be a plausible one. However we do find medical studies looking at this possibility. One such tested the progestational activity of various steroids including nandrolone, norethandrolone, methandrostenolone, testosterone and oxymetholone. It reported no significant progestational effect inherent in oxymetholone or methandrostenolone, slight activity with testosterone and strong progestational effect inherent in nandrolone and norethandrolone. With such findings it starts to seem much more likely that oxymetholone can intrinsically activate the estrogen receptor itself, similar to but more profoundly than the estrogenic androgen methAndriol. If this is the case we can only combat the estrogenic side effects of oxymetholone with estrogen receptor antagonists such as Nolvadex or Clomid, and not with an aromatase inhibitor. The strong anti-aromatase compounds such as Arimidex, Femara, or Aromasin would prove to be totally useless with this steroid, as aromatase is not involved.
Anadrol (Oxydrol) is also a very potent androgen. This factor tends to produce many pronounced, unwanted androgenic side effects. Oily skin, acne and body/facial hair growth can be seen very quickly with this drug. Many individuals respond with severe acne, often requiring medication to keep it under control. Some of these individuals find that Accutaine works well, which is a strong prescription drug that acts on the sebaceous glands to reduce the release of oils. Those with a predisposition for male pattern baldness may want to stay away from Anadrol 50 completely, as this is certainly a possible side effect during therapy. And while some very adventurous female athletes do experiment with this compound, it is much too androgenic to recommend. Irreversible virilization symptoms can be the result and may occur very quickly, possibly before you have a chance to take action.
It is interesting to note that Anadrol 50 does exhibit some tendency to convert to dihydrotestosterone, although this does not occur via the 5-alpha reductase enzyme (responsible for altering testosterone to form DHT) as it is already a dihydrotestosterone based steroid. Aside from the added c-17 alpha alkylation, oxymetholone differs from DHT only by the addition of a 2-hydroxymethylene group. This grouping can be removed metabolically however, reducing oxymetholone to the potent androgen l7alpha-methyl dihydrotestosterone (mesterolone; methyldihydrotestosterone). There is little doubt that this biotransformation contributes at least at some level to the androgenic nature of this steroid, especially when we note that in its initial state Anadrol 50 has a notably low binding affinity for the androgen receptor. So although we have the option of using the reductase inhibitor finasteride (Proscar) to reduce the androgenic nature of testosterone, it would be of no benefit with Anadrol 50 as this enzyme is not involved.
The principle drawback to Anadrol 50 (Oxydrol) is that it is a 17alpha alkylated compound. Although this design gives it the ability to withstand oral administration, it can be very stressful to the liver. Anadrol (Oxydrol) is particularly dubious because we require such a high milligram amount per dosage. The difference is great when comparing it to other oral steroids like Dianabol or Winstrol, which have the same chemical alteration. Since they have a slightly higher affinity for the androgen receptor, they are effective in much smaller doses. Anadrol 50 has a lower affinity, which may be why we have a 50mg tablet dosage. When looking at the medical requirements, the recommended dosage for all ages has been 1 - 5 mg/kg of body weight. This would give a 220lb person a dosage as high as 10 Anadrol 50 tablets (500mg) per day. There should be little wonder why when liver cancer has been linked to steroid use, Anadrol 50 (Oxydrol) is generally the culprit. Athletes actually never need such a high dosage and will take in the range of only 1-3 tablets per day. Many happily find that one tablet is all they need for exceptional results, and avoid higher amounts. Cautious users will also limit the intake of this compound to no longer than 4-6 weeks and have their liver enzymes checked regularly with a doctor. Kidney functions may also need to be looked after during longer use, as water retention/high blood pressure can take a toll on the body. Before starting a cycle, one should know to give Anadrol 50 the respect it is due. It is a very powerful drug, but not always a friendly one.
When discontinuing Anadrol 50, the crash can be equally powerful. To begin with, the level of water retention will quickly diminish, dropping the user's body weight dramatically. This should be expected, and not of much concern. What is of great concern is restoring endogenous testosterone production. Anadrol 50 will quickly and effectively lower natural levels during a cycle, so HCG and Clomid/Nolvadex are a must when discontinuing a cycle.
The old practice of slowly tapering off your dosage is totally ineffective at raising testosterone levels. Without ancillary drugs, run away cortisol levels will likely strip much of the muscle that was gained during the cycle. If HCG and Clomid/Nolvadex are used properly, the person should be able to maintain a considerable amount of new muscle mass. Before going off, some alternately choose to first switch over to a milder injectable like Deca-Durabolin. This is in an effort to harden up the new mass, and can prove to be an effective practice. Although a drop of weight due to water loss is likely when making the switch, the end result should be the retention of more (quality) muscle mass with a less pronounced crash. Remember ancillaries though, as testosterone production will not be rebounding during Deca therapy.